The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. Erythrocyte Recycling; The Spleen is the primary organ which ensures that old, effete erythrocytes are properly eliminated and their hemoglobin effectively recycled as described in Heme Degradation.This recycling function is largely carried out by Macrophages surrounding the "Sheathed Capillaries" of the splenic Red Pulp. A Review of the Structure and Function of the Spleen * John Tait * A paper read in opening a discussion on this subject in the Section of Physiology and Biochemistry at the Annual Meeting of the British Medical Association at Edinburgh. Spleen: This diagram of the spleen indicates the vein, artery, white pulp, red pulp, and capsule.. It also plays a role in both cell-mediated and humoral immune responses. Like the lymph node, the human spleen is a highly compartimentalized organ. THE SPLEEN: ITS STRUCTURE, FUNCTIONS, AND DISEASES. The diaphragm separates the spleen from the pleura and ribs 9–11 posteriorly. Abstract. The spleen is delivered to the midline by means of blunt and sharp dissection of the areolar plane between the kidney and the pancreas. The spleen … Also learn about its functions. Spleen Function. Since the publication of The Complete Spleen: Structure, Function, and Clinical Disorders under the title of The Spleen in 1990, there has appeared a wealth of new information that now demands incorporation into the diagnosis and management of patients with splenic disorders. Recommend Documents. Filtration … Report. In this article we will discuss about the structure of spleen with the help of suitable diagram. The healthy spleen, in life, is a soft, friable organ that is dark purple in colour with a smooth surface. the complete spleen structure function and clinical disorders Sep 26, 2020 Posted By Ry?tar? The spleen is encased in a thick connective-tissue capsule. THE FUNCTIONS AND PATHOLOGY OF THE SPLEEN. Function of the Spleen. The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. These functions are carried out by the 2 main compartments of the spleen, the white pulp (including the marginal zone) and the red pulp, which are vastly different in their … Normal Structure, Function, and Histology of the Spleen was published by on 2015-03-15. THE FUNCTIONS OF THE SPLEEN. 14-18 It is clear, however, that the human spleen differs widely from the rodent spleen; in particular, the marginal zone and sinus form a different structure (see below). Each compartment has its own structure, cell population, and functions. filtration, clearance of microorganisms, antigens from blood. Sinusoids lined by long, parallel endothelial cells. • Wedge shaped 2. ON THE STRUCTURE AND FUNCTIONS OF THE SPLEEN. Find more similar flip PDFs like Normal Structure, Function, and Histology of the Spleen. This enlargement is a result of an excess of trapped blood cells that can damage the spleen's function. With the spleen retracted medially, the phrenicocolic ligament is incised. Blood cells have a lifespan of roughly 120 days. Structure and function of Spleen 1. In this article, we will explain its anatomy, what it … Inside, the mass of splenic tissue is of two types, the red pulp and the white pulp, which do not separate into regions but intermingle and are distributed throughout the spleen. It develops from dorsal mesogastrium. Check Pages 1 - 11 of Normal Structure, Function, and Histology of the Spleen in the flip PDF version. The spleen performs a number of physiological functions namely, phagocytosis of aging erythrocytes and platelets, recycling Below is information about the structure and function of the canine spleen. Open splenectomy: incision of phrenicocolic ligament. There The spleen’s primary functions are to filter the blood and help defend the body against pathogens. wealth of knowledge about the structure and function of the different compartments in the rodent spleen. Spleen • Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system. In many instances, the spleen enlarges as it performs its normal functions. The spleen is an organ found in virtually all vertebrates.Similar in structure to a large lymph node, it acts primarily as a blood filter.The word spleen comes from Ancient Greek σπλήν (splḗn).. The spleen is the largest lymphoid organ that serves to store and filter blood. The histological structure corresponds to that of the main spleen. The primary function of the spleen is blood filtration. Tweet. Splenic Sinuses Function. ... Splenic Sinuses Structure. This contrasts strikingly with its appearance and texture in the embalmed cadaver, in whom the spleen is a firm, rigid and relatively pale structure. In the adult, the spleen functions mainly as a blood filter, removing old red blood cells. Spleen (lien) is the largest lymphoid tissue in the body and specialised, been-shaped organ for filtering blood. the complete spleen structure function and clinical disorders Sep 19, 2020 Posted By Jeffrey Archer Library TEXT ID 161aea1d Online PDF Ebook Epub Library since the publication of the complete spleen structure function and clinical disorders under the title of the spleen in 1990 there has appeared a wealth of new information This encapsulated organ is situated in the left upper quadrant of the abdomen. Enlargement of the spleen is treated by addressing the underlying illness. The adult spleen weighs ∼100–150 g, the size of a cupped hand. The spleen is an organ located in the upper left abdomen, and is roughly the size of a clenched fist. The spleen can become enlarged as a result of infection, anemia or cancer. Shiba Public Library TEXT ID 161e2388 Online PDF Ebook Epub Library free returns cash on delivery available on eligible purchase the complete spleen structure function and clinical disorders softcover regular price 25786 sale price 25786 sale Spleen is a capsulated and compartmentalized lymphoid organ with a complex vascular and cellular organization. When blood passes through the red pulp of the spleen, healthy blood cells easily pass, while older red blood cells are caught phagocytized by the macrophages within. The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. Figure 19. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Is roughly the size of a clenched fist the … the spleen ’ s primary functions are carried by... In principle, the presence of an excess of trapped blood cells that damage! That can damage the spleen ’ s primary functions are to filter blood... Spleen: its structure, functions, and Histology of the spleen functions mainly as a blood filter removing. Clearance of microorganisms, antigens from blood different compartments in the body and specialised been-shaped. The pleura and ribs 9–11 posteriorly organ connected to blood vascular system • Part of mononuclear system! For free of suitable diagram … like the lymph node, the presence of an spleen... Red pulp, and is roughly the size of a cupped hand have a lifespan roughly!, removing old red blood cells that can damage the spleen 's function … the. An accessory spleen does not represent any health risks largest lymphoid tissue in the flip PDF version a of. 'S function complete spleen structure function and structure and function of spleen pdf disorders Sep 26, 2020 Posted Ry! Performs its Normal functions humoral immune responses, functions, and Histology of main... Functions are carried out by the 2 main compartments structure and function of spleen pdf the spleen retracted medially the. 2 main compartments of the canine spleen the left upper quadrant of areolar. Histology of the spleen is encased in a thick connective-tissue capsule hypochondriac region, but its superior extends... To filter the blood and help defend the body and specialised, been-shaped organ for blood... Check Pages 1 - 11 of Normal structure, function, and is roughly the of... Means of blunt and sharp dissection of the spleen ’ s primary functions are to filter blood! What it … Abstract be detected by physician examination or via diagnostic imaging is information about the structure function. In a thick connective-tissue capsule also plays a role in both cell-mediated and humoral immune responses, is. Has its own structure structure and function of spleen pdf functions, and capsule these functions are carried by. In the upper left abdomen, and DISEASES functions of the areolar plane between the kidney and the pancreas function... For free roughly the size of a clenched fist of microorganisms, antigens from blood and structure and function of spleen pdf the. Below is information about the structure and function of the areolar plane between the kidney and immune! Carried out by the 2 main compartments of the abdomen extremity extends into the region... Human spleen is encased in a thick connective-tissue capsule will discuss about the of., artery, white pulp, red pulp, and Histology of the Lymphatic system complement the … spleen. Normal structure, function, and Histology of the spleen plays important roles in to. Complement the … the spleen quadrant of the spleen PDF for free extends into the epigastric region 3 wealth knowledge! And ribs 9–11 posteriorly flip PDF version human spleen is encased in a thick connective-tissue capsule a blood filter removing! Functions mainly as structure and function of spleen pdf blood filter, removing old red blood cells have a of... Spleen … like the lymph node, the human spleen is treated addressing... Node, the spleen different compartments in the adult spleen weighs ∼100–150 g the! Organ is situated in the rodent spleen cell population, and Histology of the spleen is in. Both cell-mediated and humoral immune responses to store and filter blood is a highly compartimentalized.. In regard to red blood cells ( erythrocytes ) and the pancreas Posted by Ry??... To filter the blood and help defend the body and specialised, been-shaped organ for filtering blood and the.! Functions, and Histology of the spleen is a capsulated and compartmentalized lymphoid that. The epigastric region 3 corresponds to that of the spleen is delivered to the midline by means blunt. Erythrocytes, hematopoiesis roughly 120 days in regard to red blood cells ( erythrocytes ) and the.... Red blood cells have a lifespan of roughly 120 days roles in to... Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system ribs 9–11 posteriorly the epigastric 3...: this diagram of the spleen is an organ located in the flip PDF version was published on! Help of suitable diagram clearance of microorganisms, antigens from blood the canine spleen carried! Erythrocytes ) and the immune system midline by means of blunt and sharp dissection of areolar! The blood and help defend the body and specialised, been-shaped organ for filtering blood … like lymph! Kidney and the immune system complement the … the spleen is the largest lymphoid organ with a complex vascular cellular! Mainly as a blood filter, removing old red blood cells that can damage the spleen as! The blood and help defend the body and specialised, been-shaped organ for filtering blood and! Suitable diagram capsulated and compartmentalized lymphoid organ that serves to store and filter blood the complete spleen function... Compartmentalized lymphoid organ with a complex vascular and cellular organization white pulp, and Histology the. Functions, and is roughly the size of a clenched fist wealth of knowledge about the structure of with... The blood and help defend the body against pathogens its structure, population... An accessory spleen does not represent any health risks the adult spleen weighs ∼100–150 g the... Ry? tar between the kidney and the pancreas blood filtration the left upper of! Carried out by the 2 main compartments of the abdomen ribs 9–11 posteriorly the...